Other processing mutations (class 2) that may be helped by VX809 (He et al. 2012):
A study has just been published that investigated whether VX809 might help mutations other than F508del. This paper suggests that VX809 can help the CFTR reach the surface with several other mutations. The laboratory testing found that VX809 increased the CFTR trafficking with H1054D, G1061R, L1065P, Q1071P, L1077P, H139R, R258G, and S945L. I507del and R560T were not trafficked by VX809 in this study.